Parts-per-Trillion Level Calibration of Semivolatiles Using LVI-PTV-GC/MSD Application
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چکیده
The analysis of semivolatiles in the parts-per-trillion range presents challenges due to analyte activity, background contamination, and instrument sensitivity. Method requirements vary worldwide, with the least sensitive specifying 1-μL injections and full scan data acquisition. Lower level calibrations can be achieved using large volume injection (LVI) with a programmable temperature vaporizing (PTV) inlet and the MSD operating in SIM mode. Decreased sample preparation can be used as a trade-off for these lower detection limits.
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تاریخ انتشار 2007